Video: Treatment Of Pancreatic Cancer – Ajmel Puthawala, MD

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Treatment for pancreatic cancer. Pancreatic Cancer is the fourth deadliest type of cancer in the United States and around the world. This aggressive type of cancer is often not detected until it is in its advanced stages. This cancer causes life span to be about 5 years or in some cases even lower. Cancers that develop within the pancreas fall into two major types. First are the cancers of the endocrine pancreas which is the part that makes insulin for the body. Second are the cancers of the exocrine pancreas which is the part that makes enzymes. Cancers of the exocrine pancreas develop from the cells that line the system of ducts that deliver enzymes to the small intestine and are called commonly referred to as pancreatic adenocarcinomas. Adenocarcinoma of the pancreas makes up about 95% of all pancreatic cancers and is the subject of study by the medical society.

Cells that line the ducts in the exocrine pancreas divide more rapidly than the tissues that surround them. The reasons for this are still not clear. These cells can make a mistake when they divide and an abnormal cell can be made. When an abnormal cell begins to divide in a disorganized way, a growth can form. These changes are called "dysplasia." Often, dysplastic cells can undergo extra genetic mistakes over time and become even more abnormal. If these dysplastic cells begin to invade through the walls of the duct from which they arise into the surrounding tissue, a cancer develops.

About 40,000 cases of pancreatic cancer occur yearly in the United States. Most people who develop pancreatic cancer do so without any risk factors. Perhaps the biggest risk factor is getting old. Being over the age of 60 puts an individual at greater risk for pancreatic cancer. Rarely, can there be any genetic syndromes that run in families which put individuals at higher risk for cancer. For example, African-Americans may be at greater risk as many individuals with close family members who have been previously diagnosed with the disease. Other behaviors or conditions that may put people at risk include tobacco use, obesity, an inactive lifestyle, a history of diabetes, chronic pancreatic swelling, and a rich fatty diet.